Advances in mRNA Vaccine Technology Beyond COVID-19
Neha Singh, Nikita Sherwani.
The rapid and unprecedented success of mRNA vaccines against the SARS-CoV-2 virus has revolutionized the field of vaccinology, demonstrating the immense potential of this platform. Beyond its pivotal role in combating the COVID-19 pandemic, mRNA vaccine technology is now at the forefront of a new era in medicine, with research and development expanding into a vast array of other infectious diseases, cancer, and even autoimmune and genetic disorders. This review provides a comprehensive overview of the post-COVID-19 landscape of mRNA vaccines. It delves into the fundamental technological advancements that have enhanced their stability, efficacy, and delivery. We explore the promising applications in f ighting other infectious pathogens like influenza, HIV, and RSV, and their burgeoning role in personalized cancer immunotherapy. The paper also addresses the current challenges, including manufacturing scalability, cost, and the need for improved thermostability, while outlining the future prospects of this transformative technology. The journey of mRNA vaccines, from a decades-old concept to a cornerstone of modern medicine, highlights their flexibility, speed, and potential to redefine global health.
